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Dicer Ablation in Oligodendrocytes Provokes Neuronal Impairment in Mice

OBJECTIVE: MicroRNAs (miRNAs) regulate gene expression and have many roles in the brain, but a role in oligodendrocyte (OL) function has not been demonstrated. METHODS: A Dicer floxed conditional allele was crossed with the proteolipid protein promoter-driven inducible Cre allele to generate inducib...

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Bibliographic Details
Main Authors: Shin, Daesung, Shin, Ji-Yeon, McManus, Michael T., Ptáček, Louis J., Fu, Ying-Hui
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885004/
https://ncbi.nlm.nih.gov/pubmed/20035504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21927
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