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Vaccinia virus gene F3L encodes an intracellular protein that affects the innate immune response

The Vaccinia virus BTB/kelch protein F3 has been characterized and its effects on virus replication in vitro and virus virulence in vivo have been determined. The loss of the F3L gene had no effect on virus growth, plaque phenotype or cytopathic effect in cell culture under the conditions tested. Ho...

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Bibliographic Details
Main Authors: Froggatt, Graham C., Smith, Geoffrey L., Beard, Philippa M.
Format: Artigo
Language:Inglês
Published: Society for General Microbiology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884953/
https://ncbi.nlm.nih.gov/pubmed/17554022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.82815-0
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