Cardiac alpha-myosin heavy chains differ in their induction of myocarditis. Identification of pathogenic epitopes.

BALB/c mice develop autoimmune myocarditis after immunization with mouse cardiac myosin, whereas C57B/6 mice do not. To define the immunogenicity and pathogenicity of cardiac myosin in BALB/c mice, we immunized mice with different forms of cardiac myosin. These studies demonstrate the discordance of...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Liao, L, Sindhwani, R, Leinwand, L, Diamond, B, Factor, S
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 1993
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288490/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504694/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116909
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