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Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta.

Osteopontin is a phosphorylated, sialic acid-rich, noncollagenous bone matrix protein containing the Arg-Gly-Asp-Ser amino acid sequence responsible for cell adhesion. The protein strongly binds to hydroxyapatite and play an important role in calcification. Expression of osteopontin mRNA was analyze...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Ikeda, T, Shirasawa, T, Esaki, Y, Yoshiki, S, Hirokawa, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288482/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8254036/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116901
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