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Phylogenetic assessment of alignments reveals neglected tree signal in gaps

BACKGROUND: The alignment of biological sequences is of chief importance to most evolutionary and comparative genomics studies, yet the two main approaches used to assess alignment accuracy have flaws: reference alignments are derived from the biased sample of proteins with known structure, and simu...

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Detalhes bibliográficos
Main Authors: Dessimoz, Christophe, Gil, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884540/
https://ncbi.nlm.nih.gov/pubmed/20370897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-4-r37
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