The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates.

This study examined the effect of 2 yr of treatment with the aminobisphosphonate alendronate (ALN) (0.05 or 0.25 mg/kg i.v. ALN every 2 wk) on estrogen deficiency bone loss and bone strength changes in ovariectomized (OVX) baboons (n = 7 per group) and the ALN mode of action at the tissue level. Bio...

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Bibliografiske detaljer
Main Authors: Balena, R, Toolan, B C, Shea, M, Markatos, A, Myers, E R, Lee, S C, Opas, E E, Seedor, J G, Klein, H, Frankenfield, D
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC288453/
https://ncbi.nlm.nih.gov/pubmed/8254015
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