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CagA and VacA Polymorphisms Are Associated with Distinct Pathological Features in Helicobacter pylori-Infected Adults with Peptic Ulcer and Non-Peptic Ulcer Disease

Polymorphic variability in Helicobacter pylori factors CagA and VacA contributes to bacterial virulence. The presence of one CagA EPIYA-C site is an independent risk factor for gastroduodenal ulceration (odds ratio [OR], 4.647; 95% confidence interval [CI], 2.037 to 10.602), while the presence of th...

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Detalhes bibliográficos
Main Authors: Panayotopoulou, Effrosini G., Sgouras, Dionyssios N., Papadakos, Konstantinos S., Petraki, Kalliopi, Breurec, Sébastien, Michopoulos, Spyros, Mantzaris, Gerassimos, Papatheodoridis, George, Mentis, Andreas, Archimandritis, Athanasios
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884518/
https://ncbi.nlm.nih.gov/pubmed/20392907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00662-10
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