Characterization of fHbp, nhba (gna2132), nadA, porA, and Sequence Type in Group B Meningococcal Case Isolates Collected in England and Wales during January 2008 and Potential Coverage of an Investigational Group B Meningococcal Vaccine

Invasive disease caused by meningococcal capsular groups A, C, W-135, and Y is now preventable by means of glycoconjugate vaccines that target their respective polysaccharide capsules. The capsule of group B meningococci (MenB) is poorly immunogenic and may induce autoimmunity. Vaccines based on the...

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Main Authors: Lucidarme, Jay, Comanducci, Maurizio, Findlow, Jamie, Gray, Stephen J., Kaczmarski, Edward B., Guiver, Malcolm, Vallely, Pamela J., Oster, Philipp, Pizza, Mariagrazia, Bambini, Stefania, Muzzi, Alessandro, Borrow, Ray
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Vaccine Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884420/
https://ncbi.nlm.nih.gov/pubmed/20375242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00027-10
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