Maternal MTHFR genotype and haplotype predict deficits in early cognitive development in a lead-exposed birth cohort in Mexico City(1)(2)(3)(4)

Background: Maternal folate nutritional status and prenatal lead exposure can influence fetal development and subsequent health. The methylenetetrahydrofolate reductase (MTHFR) gene is important for folate metabolism, and 2 common polymorphisms, C677T and A1298C, reduce enzymatic activity; C677T is...

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Detalhes bibliográficos
Main Authors: Pilsner, J Richard, Hu, Howard, Wright, Robert O, Kordas, Katarzyna, Ettinger, Adrienne S, Sánchez, Brisa N, Cantonwine, David, Lazarus, Alicia L, Cantoral, Alejandra, Schnaas, Lourdes, Téllez-Rojo, Martha Maria, Hernández-Avila, Mauricio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2010
Assuntos:
Nutritional Epidemiology and Public Health
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884326/
https://ncbi.nlm.nih.gov/pubmed/20504979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.2009.28839
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