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Alkylating agents and immunotoxins exert synergistic cytotoxic activity against ovarian cancer cells. Mechanism of action.

Alkylating agents can be administered in high dosage to patients with ovarian cancer using autologous bone marrow support, but drug-resistant tumor cells can still persist. Immunotoxins provide reagents that might eliminate drug resistant cells. In the present study, concurrent treatment with alkyla...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Lidor, Y J, O'Briant, K C, Xu, F J, Hamilton, T C, Ozols, R F, Bast, R C
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288428/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8227359/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116851
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