Anti-Cancer Activity of Nitrones in the Apc(Min/+) Model of Colorectal Cancer

The nitrones of α-phenyl-tert-butyl nitrone (PBN) and 4-hydroxyl-PBN (4-OH-PBN) that have anti-cancer activity in models of liver cancer and glioblastomas, were tested in the ApcMin/+ mouse model. Mice were administered PBN and 4-OH-PBN in drinking water and intestinal tumor size and number assessed...

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Detalhes bibliográficos
Main Authors: Floyd, Robert A., Towner, Rheal A., Wu, Dee, Abbott, Andrew, Cranford, Rebecca, Branch, Dan, Guo, Wei-Xing, Foster, Steven B., Jones, Inna, Alam, Rajib, Moore, Danny, Allen, Toby, Huycke, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884269/
https://ncbi.nlm.nih.gov/pubmed/19886748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715760903321796
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