The human platelet alloantigens Br(a) and Brb are associated with a single amino acid polymorphism on glycoprotein Ia (integrin subunit alpha 2).

The human GPIa/IIa complex, also known as integrin alpha 2 beta 1, serves as a major receptor for collagen in platelets and other cell types. In addition to its role in platelet adhesion to extracellular matrix, GPIa/IIa is also known to bear the clinically important Br(a) and Brb alloantigenic dete...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Santoso, S, Kalb, R, Walka, M, Kiefel, V, Mueller-Eckhardt, C, Newman, P J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288426/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7901236/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116849
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