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Polarizable Atomic Multipole X-Ray Refinement: Hydration Geometry and Application to Macromolecules

We recently developed a polarizable atomic multipole refinement method assisted by the AMOEBA force field for macromolecular crystallography. Compared to standard refinement procedures, the method uses a more rigorous treatment of x-ray scattering and electrostatics that can significantly improve th...

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Detalhes bibliográficos
Main Authors: Fenn, Timothy D., Schnieders, Michael J., Brunger, Axel T., Pande, Vijay S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884231/
https://ncbi.nlm.nih.gov/pubmed/20550911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.02.057
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