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Development of pemphigus vulgaris-like lesions in severe combined immunodeficiency disease mice reconstituted with lymphocytes from patients.

Pemphigus vulgaris is an autoimmune blistering disease that is induced by binding of antibodies to a 130/85-kD protein complex on epidermal keratinocytes. An in vivo experimental model of this disease was developed by reconstituting severe combined immunodeficiency (SCID) mice with 1-10 x 10(7) PBL...

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Main Authors: Juhasz, I, Lazarus, G S, Murphy, G F, Shih, I M, Herlyn, M
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1993
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC288423/
https://ncbi.nlm.nih.gov/pubmed/8227357
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