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Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice
While senile plaques injure neurons focally, the functional response of astrocytes to Alzheimer’s disease pathology is unknown. Using multiphoton fluorescence lifetime imaging microscopy in vivo, we quantitatively imaged astrocytic calcium homeostasis in a mouse model of Alzheimer’s disease. Resting...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884172/ https://ncbi.nlm.nih.gov/pubmed/19251629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1169096 |
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