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Effect of Mechanical Factors on the Function of Engineered Human Blood Microvessels in Microfluidic Collagen Gels

This work examines how mechanical signals affect the barrier function and stability of engineered human microvessels in microfluidic type I collagen gels. Constructs that were exposed to chronic low flow displayed high permeabilities to bovine serum albumin and 10 kDa dextran, numerous focal leaks,...

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Detalhes bibliográficos
Main Authors: Price, Gavrielle M., Wong, Keith H. K., Truslow, James G., Leung, Alexander D., Acharya, Chitrangada, Tien, Joe
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884145/
https://ncbi.nlm.nih.gov/pubmed/20537705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.04.041
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