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ErbB Inhibitory Protein [EBIP]: A Modified Ectodomain of EGFR Synergizes with Dasatinib to Inhibit Growth of Breast Cancer Cells

Many solid tumors including breast cancer show increased activation of several growth factor receptors, specifically EGFR and its family members (EGFRs) as well as c-Src, a non-receptor tyrosine kinase that promote proliferation, inhibit apoptosis and induce metastasis. We hypothesize that inhibitio...

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Bibliographische Detailangaben
Hauptverfasser: Nautiyal, Jyoti, Yu, Yingjie, Aboukameel, Amro, Kanwar, Shailender, Das, Jayanta K, Du, Jianhua, Patel, Bhaumik, Sarkar, Fazlul H., Rishi, Arun K., Mohammad, Ramzi, Majumdar, Adhip P. N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884079/
https://ncbi.nlm.nih.gov/pubmed/20515951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0019
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