Genetic Modification of Mesenchymal Stem Cells Overexpressing CCR1 Increases Cell Viability, Migration, Engraftment and Capillary Density in the Injured Myocardium

RATIONALE: Although mesenchymal stem cell (MSC) transplantation has been shown to promote cardiac repair in acute myocardial injury in vivo, its overall restorative capacity appears to be restricted mainly due to poor cell viability and low engraftment in the ischemic myocardium. Specific chemokines...

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Bibliographische Detailangaben
Hauptverfasser: Huang, Jing, Zhang, Zhiping, Guo, Jian, Ni, Aiguo, Deb, Arjun, Zhang, Lunan, Mirotsou, Maria, Pratt, Richard E, Dzau, Victor J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884066/
https://ncbi.nlm.nih.gov/pubmed/20378860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.196030
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