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Transport of beta-lactam antibiotics in kidney brush border membrane. Determinants of their affinity for the oligopeptide/H+ symporter.

This study was designed to determine whether beta-lactam antibiotics (cephalosporins and penicillins) are all substrates for the renal oligopeptide/H+ symporter and, if so, whether the transport system discriminates among the numerous beta-lactam antibiotics. We used [3H]glycylglutamine, [3H]cephale...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Principais autores: Daniel, H, Adibi, S A
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1993
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8227336/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116824
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