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Conserved cytoplasmic tyrosine residues of the gamma subunit are required for a phagocytic signal mediated by Fc gamma RIIIA.

Fc receptors for immunoglobulins are found on many cells and are important in host defense. We transfected Fc gamma RIIIA, present on macrophages and natural killer (NK) cells, into COS-1 cells to study its role in phagocytosis and calcium mobilization in the absence of other Fc gamma receptors. Hum...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Park, J G, Murray, R K, Chien, P, Darby, C, Schreiber, A D
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288377/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408660/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116804
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