Lipopolysaccharide (LPS) recognition in macrophages. Participation of LPS-binding protein and CD14 in LPS-induced adaptation in rabbit peritoneal exudate macrophages.

Exposure of rabbit peritoneal exudate macrophages (PEM) or whole blood to picomolar concentrations of LPS induces adaptation or hyporesponsiveness to LPS. Because of the importance of plasma LPS-binding protein (LBP) and the macrophage cell membrane protein CD14 in recognition of LPS, we examined th...

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Pubblicato in:	J Clin Invest
Autori principali:	Mathison, J, Wolfson, E, Steinemann, S, Tobias, P, Ulevitch, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288374/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7691891/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116801
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