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Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear.

Neutrophil adherence and/or aggregation has been implicated in ischemia reperfusion injuries. We examined the role of P-selectin in PMN-mediated injury after reperfusion of the rabbit ear. The ear was partially amputated, and then reattached leaving the central artery and vein intact. To induce isch...

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Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Winn, R K, Liggitt, D, Vedder, N B, Paulson, J C, Harlan, J M
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1993
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288372/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7691890/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116799
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