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The Alzheimer's Disease Mitochondrial Cascade Hypothesis

We first proposed the mitochondrial cascade hypothesis of sporadic Alzheimer's disease (AD) in 2004. Our core assumptions were a person's genes determine baseline mitochondrial function and durability, this durability determines how mitochondria change with advancing age, and critical chan...

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Autors principals: Swerdlow, Russell H., Burns, Jeffrey M., Khan, Shaharyar M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883665/
https://ncbi.nlm.nih.gov/pubmed/20442494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100339
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