The functional promoter polymorphism (−842G>C) in the PIN1 gene is associated with decreased risk of breast cancer in non-Hispanic white women 55 years and younger

PIN1, an isomerase that causes conformational changes in proteins, plays an important role in mammary epithelial cell growth both physiologically and pathologically. Thus, genetic variants in the PIN1 gene may alter protein function and cancer risk. We have previously demonstrated an association bet...

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Main Authors: Han, Chan H., Lu, Jiachun, Wei, Qingyi, Bondy, Melissa L., Brewster, Abenaa M., Yu, Tse-Kuan, Buchholz, Thomas A., Arun, Banu K., Wang, Li-E
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883663/
https://ncbi.nlm.nih.gov/pubmed/20033770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0682-9
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