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UDP-GLC:GLYCOPROTEIN GLUCOSYLTRANSFERASE-GLUCOSIDASE II, THE YING-YANG OF THE ER QUALITY CONTROL

The N-glycan-dependent quality control of glycoprotein folding prevents endoplasmic to Golgi exit of folding intermediates, irreparably misfolded glycoproteins and incompletely assembled multimeric complexes. It also enhances folding efficiency by preventing aggregation and facilitating formation of...

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Sonraí Bibleagrafaíochta
Main Authors: D’Alessio, Cecilia, Caramelo, Julio J., Parodi, Armando J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883647/
https://ncbi.nlm.nih.gov/pubmed/20045480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2009.12.014
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