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UDP-GLC:GLYCOPROTEIN GLUCOSYLTRANSFERASE-GLUCOSIDASE II, THE YING-YANG OF THE ER QUALITY CONTROL
The N-glycan-dependent quality control of glycoprotein folding prevents endoplasmic to Golgi exit of folding intermediates, irreparably misfolded glycoproteins and incompletely assembled multimeric complexes. It also enhances folding efficiency by preventing aggregation and facilitating formation of...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883647/ https://ncbi.nlm.nih.gov/pubmed/20045480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2009.12.014 |
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