Glucocorticoid deficiency increases phospholipase A2 activity in rats.

An important mechanism for the antiinflammatory effect of pharmacological doses of glucocorticoids is the inhibition of arachidonic acid release from phospholipids by phospholipase A2 (PLA2). As a corollary, one might predict that low endogenous concentrations of glucocorticoids favor inflammatory d...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Vishwanath, B S, Frey, F J, Bradbury, M J, Dallman, M F, Frey, B M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288364/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408650/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116791
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