Initial Evaluation of (11)C-DPA-713, a Novel TSPO PET Ligand, in Humans

Translocator protein (TSPO) is upregulated in activated microglia and thus can serve as a marker of neuroinflammation. Recently, a novel radioligand, (11)C-N,N-diethyl-2-[2-(4-methoxyphenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-3-yl]-acetamide ((11)C-DPA-713), has been described that binds to TSPO...

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Main Authors: Endres, Christopher J., Pomper, Martin G., James, Michelle, Uzuner, Ovsev, Hammoud, Dima A., Watkins, Crystal C., Reynolds, Aaron, Hilton, John, Dannals, Robert F., Kassiou, Michael
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883612/
https://ncbi.nlm.nih.gov/pubmed/19617321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.109.062265
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