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Exogenous adenosine triphosphate (ATP) preserves proximal tubule microfilament structure and function in vivo in a maleic acid model of ATP depletion.

The hallmark of ischemic acute renal failure is a rapid and early decline in proximal tubule ATP. Since we have previously shown that over half of apical microfilament losses occur within the first 5 min of experimental ischemic injury, we postulated that microfilament (F-actin) structure and cellul...

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Pubblicato in:J Clin Invest
Autore principale: Kellerman, P S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288360/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116787
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