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Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation.

We used specific antisera and immunohistochemical methods to investigate the subcellular localization and expression of Bcr, Abl, and Bcr-Abl proteins in leukemic cell lines and in fresh human leukemic and normal samples at various stages of myeloid differentiation. Earlier studies of the subcellula...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Wetzler, M, Talpaz, M, Van Etten, R A, Hirsh-Ginsberg, C, Beran, M, Kurzrock, R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288359/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408645/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116786
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