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Detection of Botulinum Neurotoxin Serotype B at Sub Mouse LD(50) Levels by a Sandwich Immunoassay and Its Application to Toxin Detection in Milk

BACKGROUND: Botulinum neurotoxin (BoNT), the causative agent of botulism, a serious neuroparylatic disease, is produced by the anaerobic bacterium Clostridium botulinum and consists of a family of seven serotypes (A-H). We previously reported production of high-affinity monoclonal antibodies to BoNT...

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Detalhes bibliográficos
Main Authors: Scotcher, Miles C., Cheng, Luisa W., Stanker, Larry H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883556/
https://ncbi.nlm.nih.gov/pubmed/20548779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011047
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