Corticotropin Releasing Factor–Induced Amygdala Gamma-Aminobutyric Acid Release Plays a Key Role in Alcohol Dependence

BACKGROUND: Corticotropin-releasing factor (CRF) and gamma-aminobutyric acid (GABA)ergic systems in the central amygdala (CeA) are implicated in the high-anxiety, high-drinking profile associated with ethanol dependence. Ethanol augments CeA GABA release in ethanol-naive rats and mice. METHODS: Usin...

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Autors principals: Roberto, Marisa, Cruz, Maureen T., Gilpin, Nicholas W., Sabino, Valentina, Schweitzer, Paul, Bajo, Michal, Cottone, Pietro, Madamba, Samuel G., Stouffer, David G., Zorrilla, Eric P., Koob, George F., Siggins, George R., Parsons, Loren H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883449/
https://ncbi.nlm.nih.gov/pubmed/20060104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.11.007
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