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Disruption of cytoskeletal structures mediates shear stress-induced endothelin-1 gene expression in cultured porcine aortic endothelial cells.

Hemodynamic shear stress alters the architecture and functions of vascular endothelial cells. We have previously shown that the synthesis of endothelin-1 (ET-1) in endothelial cells is increased by exposure to shear stress. Here we examined whether shear stress-induced alterations in cytoskeletal st...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Morita, T, Kurihara, H, Maemura, K, Yoshizumi, M, Yazaki, Y
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116757
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