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Using short-term response information to facilitate adaptive randomization for survival clinical trials

Increased survival is a common goal of cancer clinical trials. Owing to the long periods of observation and follow-up to assess patient survival outcome, it is difficult to use outcome-adaptive randomization in these trials. In practice, often information about a short-term response is quickly avail...

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Detalhes bibliográficos
Main Authors: Huang, Xuelin, Ning, Jing, Li, Yisheng, Estey, Elihu, Issa, Jean-Pierre, Berry, Donald A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883264/
https://ncbi.nlm.nih.gov/pubmed/19326367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3578
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