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Polymorphisms of the DNA repair gene MGMT and risk and progression of head and neck cancer

Methylating agents are involved in carcinogenesis, and the DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT) removes methyl group from O(6)-methylguanine. Genetic variation in DNA repair genes has been shown to contribute to susceptibility to squamous cell carcinoma of the head and...

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Библиографические подробности
Главные авторы: Zhang, Zhengdong, Wang, Luo, Wei, Sheng, Liu, Zhengshen, Wang, Li-E, Sturgis, Erich, Wei, Qingyi
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883263/
https://ncbi.nlm.nih.gov/pubmed/20206583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.02.006
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