Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset.

The immunological mechanisms involved in maintenance of an asymptomatic microfilaremic state (MF) in patients with lymphatic filariasis remain undefined. MF patients have impaired filarial antigen (Ag)-specific lymphocyte proliferation and decreased frequencies (Fo) of Ag-specific T cells, and yet e...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: King, C L, Mahanty, S, Kumaraswami, V, Abrams, J S, Regunathan, J, Jayaraman, K, Ottesen, E A, Nutman, T B
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288325/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8408619/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116752
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