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Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset.

The immunological mechanisms involved in maintenance of an asymptomatic microfilaremic state (MF) in patients with lymphatic filariasis remain undefined. MF patients have impaired filarial antigen (Ag)-specific lymphocyte proliferation and decreased frequencies (Fo) of Ag-specific T cells, and yet e...

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Autori principali: King, C L, Mahanty, S, Kumaraswami, V, Abrams, J S, Regunathan, J, Jayaraman, K, Ottesen, E A, Nutman, T B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC288325/
https://ncbi.nlm.nih.gov/pubmed/8408619
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