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Production of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos

The production of mouse chimeras is a common step in the establishment of genetically modified animal strains. Chimeras also provide a powerful experimental tool for following cell behavior during both prenatal and postnatal development. This protocol outlines a simple and economical technique for t...

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Bibliografiske detaljer
Main Authors: Eakin, Guy S, Hadjantonakis, Anna-Katerina
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883166/
https://ncbi.nlm.nih.gov/pubmed/17406396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2006.173
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