Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy

BACKGROUND AND AIMS: DNA ploidy abnormalities (aneuploidy/tetraploidy) measured by flow cytometry (FC) are strong predictors of future cancer development in untreated Barrett's oesophagus, independent of histology grade. Image cytometric DNA analysis (ICDA) is an optical technique allowing visu...

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Detalhes bibliográficos
Main Authors: Dunn, J M, Mackenzie, G D, Oukrif, D, Mosse, C A, Banks, M R, Thorpe, S, Sasieni, P, Bown, S G, Novelli, M R, Rabinovitch, P S, Lovat, L B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883155/
https://ncbi.nlm.nih.gov/pubmed/20461081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605688
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