Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4(+) T cells independently of CCR6

β-Defensins comprise a family of cationic, antimicrobial and chemoattractant peptides. The six cysteine canonical motif is retained throughout evolution and the disulphide connectivities stabilise the conserved monomer structure. A murine β-defensin gene (Defr1) present in the main defensin cluster...

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Autores principales: Taylor, Karen, Rolfe, Mark, Reynolds, Natalie, Kilanowski, Fiona, Pathania, Uday, Clarke, Dave, Yang, De, Oppenheim, Joost, Samuel, Kay, Howie, Sarah, Barran, Perdita, Macmillan, Derek, Campopiano, Dominic, Dorin, Julia
Formato: Artigo
Lenguaje:Inglês
Publicado: WILEY-VCH Verlag 2009
Materias:
Innate immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883079/
https://ncbi.nlm.nih.gov/pubmed/19404978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838566
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