Analysis of single nucleotide polymorphisms in the NOS2A gene and interaction with smoking in age-related macular degeneration

Age-related macular degeneration (AMD) is a complex degenerative retinal disease influenced by both genetic and environmental risk factors. We assessed whether single nucleotide polymorphisms (SNPs) in the NOS2A gene increase risk and modulate the effect of smoking in AMD. 998 Caucasian subjects (71...

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Autori principali: AYALA-HAEDO, JUAN A., GALLINS, PAUL J., WHITEHEAD, PATRICE L., SCHWARTZ, STEPHEN G., KOVACH, JACLYN L., POSTEL, ERIC A., AGARWAL, ANITA, WANG, GAOFENG, HAINES, JONATHAN L., PERICAK-VANCE, MARGARET A., SCOTT, WILLIAM K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882995/
https://ncbi.nlm.nih.gov/pubmed/20374233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2010.00570.x
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