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Social isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult rats

Social deprivation in early life disrupts emotionality and attentional processes in humans. Rearing rats in isolation reproduces some of these abnormalities, which are attenuated by daily handling. However, the neurochemical mechanisms underlying these responses remain poorly understood. We hypothes...

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Detalhes bibliográficos
Main Authors: Sciolino, Natale R., Bortolato, Marco, Eisenstein, Sarah A., Fu, Jin, Oveisi, Fariba, Hohmann, Andrea G., Piomelli, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882942/
https://ncbi.nlm.nih.gov/pubmed/20394803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.04.007
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