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Expression, purification, crystallization and preliminary X-ray analysis of ORF60, the small subunit (R2) of ribonucleotide reductase from Kaposi’s sarcoma-associated herpesvirus (KSHV)

Ribonucleotide reductase (RNR) is responsible for converting ribonucleotides to deoxyribonucleotides, which are the building blocks of DNA. The enzyme is present in all life forms as well as in some large DNA viruses such as herpesviruses. The α-herpesviruses and γ-herpesviruses encode two class Ia...

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Detalhes bibliográficos
Main Authors: Gurmu, Daniel, Dahlroth, Sue-Li, Haas, Juergen, Nordlund, Pär, Erlandsen, Heidi
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882783/
https://ncbi.nlm.nih.gov/pubmed/20516613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110016052
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