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Crystallization and preliminary X-ray crystallographic studies of a Lys49-phospholipase A(2) homologue from Bothrops pirajai venom complexed with rosmarinic acid

PrTX-I, a noncatalytic and myotoxic Lys49-phospholipase A(2) from Bothrops pirajai venom, was crystallized in the presence of the inhibitor rosmarinic acid (RA). This is the active compound in the methanolic extract of Cordia verbenacea, a plant that is largely used in Brazilian folk medicine. The c...

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Autori principali: dos Santos, Juliana I., Santos-Filho, Norival A., Soares, Andreimar M., Fontes, Marcos R. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882773/
https://ncbi.nlm.nih.gov/pubmed/20516603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110013709
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