Inflammation and insulin resistance induced by trans-10, cis-12 conjugated linoleic acid depend on intracellular calcium levels in primary cultures of human adipocytes

We previously demonstrated that trans-10, cis-12 (10,12) conjugated linoleic acid (CLA) induced inflammation and insulin resistance in primary human adipocytes by activating nuclear factor κB (NFκB) and extracellular signal-related kinase (ERK) signaling. In this study, we demonstrated that the init...

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Bibliografiske detaljer
Main Authors: Kennedy, Arion, Martinez, Kristina, Chung, Soonkyu, LaPoint, Kathy, Hopkins, Robin, Schmidt, Soren F., Andersen, Kenneth, Mandrup, Susanne, McIntosh, Michael
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2010
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882722/
https://ncbi.nlm.nih.gov/pubmed/20154361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M005447
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