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Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway

We determined the acute effects of oxidative stress on glucose uptake and intracellular signaling in skeletal muscle by incubating muscles with reactive oxygen species (ROS). Xanthine oxidase (XO) is a superoxide-generating enzyme that increases ROS. Exposure of isolated rat extensor digitorum longu...

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Библиографические подробности
Главные авторы: Higaki, Yasuki, Mikami, Toshio, Fujii, Nobuharu, Hirshman, Michael F., Koyama, Katsuhiro, Seino, Tetsuya, Tanaka, Keitaro, Goodyear, Laurie J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882683/
https://ncbi.nlm.nih.gov/pubmed/18303121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00150.2007
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