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Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells.

The antiviral activity of azidothymidine (AZT), dideoxycytidine (ddC), and dideoxyinosine (ddI) against HIV-1 was comparatively evaluated in PHA-stimulated PBM. The mean drug concentration which yielded 50% p24 Gag negative cultures were substantially different: 0.06, 0.2, and 6 microM for AZT, ddC,...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Gao, W Y, Shirasaka, T, Johns, D G, Broder, S, Mitsuya, H
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288239/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8387546/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116463
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