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5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers.

Neutrophil transmigration across intestinal epithelia is thought to contribute to epithelial dysfunction and characterizes many inflammatory intestinal diseases. Neutrophils activated by factors, normally present in the lumen, release a neutrophil-derived secretagogue activity to which intestinal ep...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Madara, J L, Patapoff, T W, Gillece-Castro, B, Colgan, S P, Parkos, C A, Delp, C, Mrsny, R J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288238/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8486793/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116462
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