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A Switch from a Gradient to a Threshold Mode in the Regulation of a Transcriptional Cascade Promotes Robust Execution of Meiosis in Budding Yeast

Tight regulation of developmental pathways is of critical importance to all organisms, and is achieved by a transcriptional cascade ensuring the coordinated expression of sets of genes. We aimed to explore whether a strong signal is required to enter and complete a developmental pathway, by using me...

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Detalhes bibliográficos
Main Authors: Gurevich, Vyacheslav, Kassir, Yona
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882377/
https://ncbi.nlm.nih.gov/pubmed/20543984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011005
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