Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium.

The mechanism by which soluble mediators of immune cell origin depress myocardial contractility, either globally as in systemic sepsis, or regionally in areas of inflammatory myocardial infiltrates, remains unclear. When freshly isolated ventricular myocytes from adult rat hearts were preincubated f...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Balligand, J L, Ungureanu, D, Kelly, R A, Kobzik, L, Pimental, D, Michel, T, Smith, T W
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8486792/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116461
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