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Protamine and protamine-insulins exacerbate the vascular response to injury.

Endothelial cells and smooth muscle cells produce heparinlike compounds that are growth inhibitory for vascular smooth muscle cells, and it has been suggested that these compounds play a regulatory role that is perturbed with vascular injury. Indeed, exogenous heparin preparations effectively suppre...

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Pubblicato in:J Clin Invest
Autori principali: Edelman, E R, Pukac, L A, Karnovsky, M J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8486791/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116460
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